Prokaryotes also Protect their RNAs - New Types of 5' RNA Caps

Page: 414

H. Cahová

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague

Keywords: 5'-RNA cap, NAD-RNA, RNA chemical modification


It was long time pressumed that only eukaryotes protect their RNA by 5'-RNA cap. Recently, it was shown that also prokaryotes employ some kind of protection of their RNA in the form of 5'-triphosphate or NAD covalently attached to 5'-terminus. This review discusses the state of art of 5'-RNA cap in eukaryotes and prokaryotes.


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