‘Omics’ Techniques: Genomics, Transcriptomics, Proteomics and Metabolomics in Embryo Developmental Capacity Assessment
aDepartment of Biochemistry, Faculty of Science, Masaryk University, Brno, b Department of Obstetrics and Gynecology, Faculty of Medicine and University Hospital of Masaryk University, Brno
Keywords: assisted reproduction, human embryo, in vitro fertilization, genomics, transcriptomics, proteomics, metabolomics
This review defines limits of currently used techniques to assess developmental capacity of human embryos in assisted reproduction and provides an overview of techniques assessing embryo’s physiology on levels of genomics, transcriptomics, proteomics and metabolomics. Basic principles of respective techniques are included. Discovered biomarkers are discussed with respect to biochemical functions and their prognostic values of embryonal development.
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