Alternative in silico Methods for Toxicity Testing of Chemical Compounds

Autoři

  • M. Tichý National Health Institute, Šrobárova 48, 100 42 Praha 10,
  • Z. Roth National Health Institute, Šrobárova 48, 100 42 Praha 10,
  • K. Bláha Section of Environmental Hazards, Ministry of Environment, Praha,
  • A. P. Worth European Centre for Validation of Alternative Methods, Joint Research Centre, European Commission, 21020 Ispra, Italy

Abstrakt

The aim of this contribution is to review trends, demands, criteria, possibilities and limitations in the identification of hazard associated with chemical compounds and chemical preparations and to outline the legislation and alternative methods in testing toxicity of chemicals, in particular QSAR methods and models and their use for regulatory purposes.

Publikováno

15.11.2005

Jak citovat

Tichý, M., Roth, Z., Bláha, K., & Worth, A. P. (2005). Alternative in silico Methods for Toxicity Testing of Chemical Compounds. Chemické Listy, 99(10). Získáno z http://ww.w.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/1983

Číslo

Sekce

Články