Kotranslační děje aneb první okamžiky života proteinu


  • M. H. Kolář Ústav fyzikální chemie, Vysoká škola chemicko-technologická v Praze, Praha

Klíčová slova:

ribozom, ribozomální tunel, sbalování proteinů, antibiotika, translační uvěznění, zastavení ribozomu, kotranslační děje


Proteins are biopolymers composed of amino acids. Proteins play a role almost in all processes in living organisms. In cells, proteins are synthesized on ribosomes in a process called translation, where amino acids are connected one at a time by a chemical bond according to a pre-defined scenario stored as the genetic information. Relative to their lifetime, proteins spend non-negligible time attached to the ribosome. This review focuses on phenomena that involve a nascent protein before it is released from the ribosome, i.e., in the first moments of their own synthesis, co-translationally. The text partly covers a lecture given by the author at the Summer School for High School Teachers and Students organized by UCT Prague in August 2021.




Jak citovat

Kolář, M. H. (2021). Kotranslační děje aneb první okamžiky života proteinu. Chemické Listy, 115(10), 550–553. Získáno z http://ww.w.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/3941