Determination of Toxicity of Binary Mixtures Using Rat Hepatocytes

Autoři

  • A. Pokorná National Institute of Public Health, Prague
  • M. Tichý National Institute of Public Health, Prague
  • J. Nerudová National Institute of Public Health, Prague
  • J. Tumová National Institute of Public Health, Prague
  • I. Hanzlíková National Institute of Public Health, Prague

Abstrakt

Primary hepatocyte assay was used to determine acute toxicity of nickel(II) chloride - 3,4-dichloroaniline and nickel(II) chloride - sodium diclophenac mixtures. Although the components act by different mechanisms, their acute toxicity was almost additive; it decreased to zero in dependence on the molar ratio of the components. Toxicities of pollutants in environment may decrease due to interactions with other components.

Publikováno

15.08.2009

Jak citovat

Pokorná, A., Tichý, M., Nerudová, J., Tumová, J., & Hanzlíková, I. (2009). Determination of Toxicity of Binary Mixtures Using Rat Hepatocytes. Chemické Listy, 103(7). Získáno z http://ww.w.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/1517

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