Cocrystallization Screening: Advantages and Pitfalls of Particular Cocrystallization Techniques

Authors

  • V. Sládková Department of Solid State Chemistry, Institute of Chemical Technology, Prague, Czech Republic
  • B. Kratochvíl Department of Solid State Chemistry, Institute of Chemical Technology, Prague, Czech Republic
  • E. Dorozhko Tomsk Polytechnic University, Tomsk, Russia

Keywords:

medicinal substances, pharmaceutical cocrystals, screening, solid phase, crystallization

Abstract

The most common cocrystallization techniques are introduced and their pros and cons are discussed. Many cocrystallization methods have been described but none of them are universally applicable. The methods can be divi­ded into solvent-based and solvent-free methods. The choice of potential cocrystals also contributes to the effectivity of the cocrystallization screening of API (Active Pharmaceutical Ingredience). Cocrystals are an appealing option in drug formulation.

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Published

2014-11-15

How to Cite

Sládková, V., Kratochvíl, B., & Dorozhko, E. (2014). Cocrystallization Screening: Advantages and Pitfalls of Particular Cocrystallization Techniques. Chemické Listy, 108(11), 1018–1023. Retrieved from http://ww.w.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/432

Issue

Vol. 108 No. 11 (2014)

Section

Articles

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