Vliv podmínek skladování na vybrané vlastnosti oxycelulosy
Klíčová slova:oxycelulosa, hemostatikum, podmínky skladování, povrchová analýza, rentgenová fotoelektronová spektroskopie, skenovací elektronová mikroskopie, antibakteriální vlastnosti
In this research, influence of storage conditions on properties of oxidized cellulose was studied with respect to its haemostatic function. The aim was to examine changes of the properties of oxidized cellulose stored properly and that stored at laboratory conditions for 2 years. We studied surface morphology and chemical composition, as well as absorption of the simulated body fluid, behaviour in aqueous environment via potentiometric measurement of pH, and antimicrobial activity in vitro on the S. epidermidis bacteria. It was found out that the material properties of oxidized cellulose did not deteriorate. Higher absorption of simulated body fluid, lower pH in water and simulated body fluid represented positive changes with respect to the haemostatic function. Due to the acidic nature of the material, degraded oxidized cellulose preserved its antibacterial properties.