Advanced NMR Spectroscopy Methods for Study of Structure and Properties of Small Molecules

The author is the winner of the Otto Wichterle Prize 2021; the article was written at the invitation of the editor-in-chief on the occasion of the award

Authors

  • Eliška Procházková Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic https://orcid.org/0000-0002-4768-3422

DOI:

https://doi.org/10.54779/chl20220395

Keywords:

³¹P NMR, photoswitches, conformational analysis, NMR spectroscopy, polymorphism, stereochemistry

Abstract

NMR spectroscopy is the key analytical method for determination of chemical structure and investigation of physico-chemical properties, such as non-covalent interactions, tautomeric equilibria or polymorphism. In this work, selected examples of using advanced NMR methods in structural analysis are discussed. (1) NMR spectroscopy with in situ irradiation useful to monitor photochemical processes, (2) 31P NMR spectroscopy for reaction monitoring and probing stereochemistry and (3) solid-state NMR spectroscopy to investigate polymorphism.

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Published

2022-07-15

How to Cite

Procházková, E. (2022). Advanced NMR Spectroscopy Methods for Study of Structure and Properties of Small Molecules: The author is the winner of the Otto Wichterle Prize 2021; the article was written at the invitation of the editor-in-chief on the occasion of the award. Chemické Listy, 116(7), 395–404. https://doi.org/10.54779/chl20220395

Issue

Vol. 116 No. 7 (2022)

Section

Articles